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Figure 1 Kaplan-Meier Estimates of Disease-Free SurvivalAll Randomized Population)

Figure 1 Kaplan-Meier Estimates of Disease-Free SurvivalAll Randomized Population)

Nausealoss of appetiteeating much less than usualvomitingmore than once in 24 hourssevere diarrheamore than 4 times per dayor during the nightbloodyblackor tarry stoolscoughing up blood or vomit that looks like coffee groundsfeverchillsbody achesflu symptomseasy bruising or.

Table 19 Response Rates in Doubly-Resistant Patients Single-Arm Breast Cancer Trial.

XELODA is indicated as a single agent for adjuvant treatment in patients with DukesC colon cancer who have undergone complete resection of the primary tumor when treatment with fluoropyrimidine therapy alone is preferredXELODA was non-inferior to 5-fluorouracil and leucovorin5-FU/LVfor disease-free survivalDFSPhysicians should consider results of combination chemotherapy trialswhich have shown improvement in DFS and OSwhen prescribing single-agent XELODA in the adjuvant treatment of DukesC colon cancerXELODA is indicated as first-line treatment of patients with metastatic colorectalcarcinoma when treatment with fluoropyrimidine therapy alone is preferredCombination chemotherapy has shown a survival benefit compared to 5-FU/LV aloneA survival benefit over 5-FU/LV has not been demonstrated with XELODA monotherapyUse of XELODA instead of 5-FU/LV in combinations has not been adequately studied to assure safety or preservation of the survival advantage.

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